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Amy Schumer explains why she underwent drastic weight change

Amy Schumer opens up about Cushing’s syndrome on Call Her Daddy podcast
  • Amy Schumer revealed she lost 50 pounds, stating it was to "survive" after being diagnosed with Cushing syndrome, a condition caused by excessive cortisol.
  • The comedian clarified that her changed appearance was due to the resolution of her Cushing syndrome, which can cause facial puffiness, and not from Botox or fillers.
  • Schumer confirmed she used injectable medications like Mounjaro for weight loss, noting she is now "pain-free" and able to play with her son.
  • She previously tried Ozempic three years ago, losing 30 pounds, but stopped due to severe side effects, including being "bedridden" with nausea.
  • Schumer also addressed speculation about her relationship with husband Chris Fischer, stating that any issues are unrelated to her weight loss or his autism diagnosis.
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