This move is a response to threats from the Trump administration to impose new tariffs on the UK over what it perceives as anti-competitive drug pricing practices.
Raising the NICE threshold would mean the UK pays more for medicines, despite resistance from the Treasury due to a lack of direct benefits.
Officials briefed the Trump administration on these proposals earlier this week, aiming to avoid tariffs as high as 100 per cent on pharmaceutical imports.
A UK government spokesperson confirmed advanced discussions with the US administration to secure the best outcome for the UK's pharmaceutical industry and the NHS.