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This symptom could be an early biomarker for Alzheimer’s

The Conversation Original report by Jannette Rodríguez Pallares
5 early signs of Alzheimer’s you shouldn’t ignore
  • The loss of smell can occur years before the onset of symptoms for neurodegenerative diseases like Alzheimer's and Parkinson's.
  • This often underestimated symptom could serve as a vital early biomarker, enabling earlier diagnosis and potentially more effective treatments for these conditions.
  • In Parkinson's disease, significant neuron damage happens before typical motor symptoms appear, highlighting the importance of early indicators such as smell loss.
  • Research suggests that the damage-causing smell loss may originate in specific brain regions, such as the olfactory bulb or locus coeruleus, making it a “window into the brain”.
  • Specific olfactory changes, including selective smell perception and hallucinations, are observed in Parkinson's patients, with some individuals even possessing the ability to detect a unique 'Parkinson's scent'.
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