Stewart, who recently directed The Chronology of Water, highlighted the pervasive issue of gender inequality in Hollywood, stating the business is "in a state of emergency".
She spoke about the "violence of silencing" and the anger women feel, advocating for "hard truths" to become "springboards to freedom".
The event, sponsored by Chanel, also celebrated the Academy Gold Fellowship for Women, a programme supporting emerging female filmmakers.
Oscar-winning costume designer Ruth E. Carter presented the fellowship awards and emphasised the crucial role of mentorship in bridging aspiration and opportunity for women in the industry.