His wife, Kimberly, said he "passed peacefully" and faced his final days with "courage, faith, and grace” in a statement confirming his death Wednesday.
Van Der Beek shared his final social media video on January 15.
He was reflecting on New Year's resolutions, expressing his intention to spend early 2026 "recovering and resting" before focusing on goals in the spring.
Van Der Beek was battling cancer before he died and he leaves behind six children.
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